Hereditary spastic paraplegia: clinical features and pathogenetic mechanisms
Hereditary spastic paraplegia: clinical features and pathogenetic mechanisms
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Publisher
England: Elsevier Ltd
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Language
English
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Publisher
England: Elsevier Ltd
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Summary Hereditary spastic paraplegia (HSP) describes a heterogeneous group of genetic neurodegenerative disorders in which the most severely affected neurons are those of the spinal cord. These disorders are characterised clinically by progressive spasticity and weakness of the lower limbs, and pathologically by retrograde axonal degeneration of t...
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Full title
Hereditary spastic paraplegia: clinical features and pathogenetic mechanisms
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TN_cdi_proquest_miscellaneous_879482569
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_879482569
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ISSN
1474-4422
E-ISSN
1474-4465
DOI
10.1016/S1474-4422(08)70258-8