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Hereditary spastic paraplegia: clinical features and pathogenetic mechanisms

Hereditary spastic paraplegia: clinical features and pathogenetic mechanisms

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_879482569

Hereditary spastic paraplegia: clinical features and pathogenetic mechanisms

About this item

Full title

Hereditary spastic paraplegia: clinical features and pathogenetic mechanisms

Publisher

England: Elsevier Ltd

Journal title

Lancet neurology, 2008-12, Vol.7 (12), p.1127-1138

Language

English

Formats

Publication information

Publisher

England: Elsevier Ltd

More information

Scope and Contents

Contents

Summary Hereditary spastic paraplegia (HSP) describes a heterogeneous group of genetic neurodegenerative disorders in which the most severely affected neurons are those of the spinal cord. These disorders are characterised clinically by progressive spasticity and weakness of the lower limbs, and pathologically by retrograde axonal degeneration of t...

Alternative Titles

Full title

Hereditary spastic paraplegia: clinical features and pathogenetic mechanisms

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_879482569

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_879482569

Other Identifiers

ISSN

1474-4422

E-ISSN

1474-4465

DOI

10.1016/S1474-4422(08)70258-8

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