Chiral analyses of dextromethorphan/levomethorphan and their metabolites in rat and human samples us...
Chiral analyses of dextromethorphan/levomethorphan and their metabolites in rat and human samples using LC-MS/MS
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Publisher
Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag
Journal title
Language
English
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Publisher
Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag
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Contents
In order to develop an analytical method for the discrimination of dextromethorphan (an antitussive medicine) from its enantiomer, levomethorphan (a narcotic) in biological samples, chiral analyses of these drugs and their O-demethyl and/or N-demethyl metabolites in rat plasma, urine, and hair were carried out using LC-MS/MS. After the i.p. adminis...
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Full title
Chiral analyses of dextromethorphan/levomethorphan and their metabolites in rat and human samples using LC-MS/MS
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Record Identifier
TN_cdi_proquest_miscellaneous_880656668
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_880656668
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ISSN
1618-2642
E-ISSN
1618-2650
DOI
10.1007/s00216-011-4707-y
