The naïve airway hyperresponsiveness of the A/J mouse is Kit-mediated
The naïve airway hyperresponsiveness of the A/J mouse is Kit-mediated
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
There is a wide variation among humans and mice in airway hyperresponsiveness (AHR) in the absence of allergen sensitization, i.e., naïve AHR. Because mast cell (MC) activation is thought to mediate AHR in atopic asthmatic subjects, we asked whether MCs mediate naïve AHR in A/J mice. We generated an A/J congenic strain lacking c-Kit by introgressio...
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Full title
The naïve airway hyperresponsiveness of the A/J mouse is Kit-mediated
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TN_cdi_proquest_miscellaneous_881087051
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_881087051
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1106582108
