Induction of a potent immune response in the elderly using the TLR-5 agonist, flagellin, with a reco...
Induction of a potent immune response in the elderly using the TLR-5 agonist, flagellin, with a recombinant hemagglutinin influenza–flagellin fusion vaccine (VAX125, STF2.HA1 SI)
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Kidlington: Elsevier Ltd
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Language
English
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Kidlington: Elsevier Ltd
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AbstractBackgroundInfluenza vaccines perform poorly in the elderly with reduced serological response and vaccine efficacy. We evaluated a novel influenza vaccine consisting of the globular head of the HA1 domain of the A/Solomon Islands/3/2006 (H1N1) influenza virus (VAX125) genetically fused to the TLR5 ligand, flagellin, and produced in Escherich...
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Full title
Induction of a potent immune response in the elderly using the TLR-5 agonist, flagellin, with a recombinant hemagglutinin influenza–flagellin fusion vaccine (VAX125, STF2.HA1 SI)
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TN_cdi_proquest_miscellaneous_883025986
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_883025986
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ISSN
0264-410X
E-ISSN
1873-2518
DOI
10.1016/j.vaccine.2011.05.001
