Direct measurement of DNA affinity landscapes on a high-throughput sequencing instrument
Direct measurement of DNA affinity landscapes on a high-throughput sequencing instrument
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Nutiu
et al
. repurpose an Illumina sequencer to quantitatively measure binding affinities between protein and DNA. The data reveal the complex interdependency among binding motif positions and allow improved prediction of gene expression.
Several methods for characterizing DNA-protein interactions are available
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Full title
Direct measurement of DNA affinity landscapes on a high-throughput sequencing instrument
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TN_cdi_proquest_miscellaneous_883048387
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_883048387
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ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/nbt.1882
