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miR-124a is required for hippocampal axogenesis and retinal cone survival through Lhx2 suppression

miR-124a is required for hippocampal axogenesis and retinal cone survival through Lhx2 suppression

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_886917889

miR-124a is required for hippocampal axogenesis and retinal cone survival through Lhx2 suppression

About this item

Full title

miR-124a is required for hippocampal axogenesis and retinal cone survival through Lhx2 suppression

Publisher

New York: Nature Publishing Group US

Journal title

Nature neuroscience, 2011-09, Vol.14 (9), p.1125-1134

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

The authors investigate the
in vivo
function of microRNA-124a by specifically disrupting
Rncr3
, the dominant source of miR-124a in mice. Their results suggest that miR-124a is important for maturation and survival of dentate gyrus neurons and retinal cones and acts by repressing Lhx2 translation.
MicroRNA-124a (miR-124a) is the most...

Alternative Titles

Full title

miR-124a is required for hippocampal axogenesis and retinal cone survival through Lhx2 suppression

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_886917889

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_886917889

Other Identifiers

ISSN

1097-6256

E-ISSN

1546-1726

DOI

10.1038/nn.2897

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