TSLP promotes interleukin-3-independent basophil haematopoiesis and type 2 inflammation
TSLP promotes interleukin-3-independent basophil haematopoiesis and type 2 inflammation
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Siracusa, Mark C. , Saenz, Steven A. , Hill, David A. , Kim, Brian S. , Headley, Mark B. , Doering, Travis A. , Wherry, E. John , Jessup, Heidi K. , Siegel, Lori A. , Kambayashi, Taku , Dudek, Emily C. , Kubo, Masato , Cianferoni, Antonella , Spergel, Jonathan M. , Ziegler, Steven F. , Comeau, Michael R. and Artis, David
Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
TSLP's role in allergy
The cytokine thymic stromal lymphopoietin (TSLP) has been described as the master switch of allergic inflammation. Here, TSLP is shown to induce the development of basophils from bone-marrow progenitors and to activate peripheral basophils in an interleukin-3 (IL-3)-independent manner. Basophils elicited by TSLP differ fro...
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Full title
TSLP promotes interleukin-3-independent basophil haematopoiesis and type 2 inflammation
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TN_cdi_proquest_miscellaneous_888336370
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_888336370
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature10329
