Small molecule inhibitors reveal Niemann–Pick C1 is essential for Ebola virus infection
Small molecule inhibitors reveal Niemann–Pick C1 is essential for Ebola virus infection
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Filovirus infectivity factors
The extraordinary virulence of the Ebola and Marburg filoviruses has spurred intensive research into the molecular mechanisms by which they multiply and cause disease. Carette
et al
. use a genome-wide genetic screen in human cells to identify factors required for entry of Ebola virus. The screen uncovered 67...
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Full title
Small molecule inhibitors reveal Niemann–Pick C1 is essential for Ebola virus infection
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TN_cdi_proquest_miscellaneous_890676417
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_890676417
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature10380
