Multiple mutations in the Kras gene in colorectal cancer: review of the literature with two case rep...
Multiple mutations in the Kras gene in colorectal cancer: review of the literature with two case reports
About this item
Full title
Author / Creator
Publisher
Berlin/Heidelberg: Springer-Verlag
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer-Verlag
Subjects
More information
Scope and Contents
Contents
Purpose
Kras
mutations are negative predictors of anti-EGFR therapy, occurring in 40% of colorectal carcinomas (CRCs). Point substitutions in codon 12 or 13 are the most frequent mutations in
Kras
, but multiple mutations (MMs) in other codons can also develop. Few data exist on MMs with regard to their frequency and the codons and amin...
Alternative Titles
Full title
Multiple mutations in the Kras gene in colorectal cancer: review of the literature with two case reports
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_893308732
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_893308732
Other Identifiers
ISSN
0179-1958
E-ISSN
1432-1262
DOI
10.1007/s00384-011-1238-0
