Association between CYP2C1917 and metabolism of amitriptyline, citalopram and clomipramine in Dutch...
Association between CYP2C1917 and metabolism of amitriptyline, citalopram and clomipramine in Dutch hospitalized patients
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Polymorphisms in genes coding for drug metabolizing enzymes, such as the cytochrome P450 enzymes CYP2C19 and CYP2D6, can lead to therapy failure and side effects. In earlier studies, the novel variant
CYP2C19*17
increased metabolism of several CYP2C19 substrates. The objective of this study was to evaluate the impact of
CYP2C19*17
on th...
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Full title
Association between CYP2C1917 and metabolism of amitriptyline, citalopram and clomipramine in Dutch hospitalized patients
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TN_cdi_proquest_miscellaneous_895858591
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_895858591
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ISSN
1470-269X
E-ISSN
1473-1150
DOI
10.1038/tpj.2010.39
