Detrimental effects of dual ACEI–ARB therapy: is the (pro)renin receptor the culprit?
Detrimental effects of dual ACEI–ARB therapy: is the (pro)renin receptor the culprit?
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United States: Elsevier Inc
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Language
English
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Publisher
United States: Elsevier Inc
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Contents
Chan et al. report increased mortality with angiotensin-converting enzyme inhibitors and angiotensin type 1 receptor blockers in hemodialysis patients, supporting emerging evidence that such dual therapy may be detrimental. We speculate that effects of reactive renin and prorenin release on the (pro)renin receptor may explain this apparent paradox,...
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Full title
Detrimental effects of dual ACEI–ARB therapy: is the (pro)renin receptor the culprit?
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TN_cdi_proquest_miscellaneous_898507812
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_898507812
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ISSN
0085-2538
E-ISSN
1523-1755
DOI
10.1038/ki.2011.264
