Endocytosed BCRs sequentially regulate MAPK and Akt signaling pathways from intracellular compartmen...
Endocytosed BCRs sequentially regulate MAPK and Akt signaling pathways from intracellular compartments
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Antigen recognition by surface immunoglobulin triggers downstream signaling and endocytosis of B cell antigen receptors. Pierce and colleagues show that distinct kinase-activation patterns distinguish surface receptor signaling from that of internalized receptors.
Binding of antigen to the B cell antigen receptor (BCR) triggers both BCR signalin...
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Full title
Endocytosed BCRs sequentially regulate MAPK and Akt signaling pathways from intracellular compartments
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TN_cdi_proquest_miscellaneous_900626425
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_900626425
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ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni.2116
