A motif in the V3 domain of the kinase PKC-θ determines its localization in the immunological synaps...
A motif in the V3 domain of the kinase PKC-θ determines its localization in the immunological synapse and functions in T cells via association with CD28
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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The kinase PKC-θ translocates to the center of the immune synapse, but the molecular basis of this interaction is unclear. Altman and colleagues identify a conserved proline-rich motif in the V3 domain of PKC-θ required for its association with CD28 and localization to the immunological synapse.
Protein kinase C-θ (PKC-θ) translocates to the cen...
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Full title
A motif in the V3 domain of the kinase PKC-θ determines its localization in the immunological synapse and functions in T cells via association with CD28
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TN_cdi_proquest_miscellaneous_900626430
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_900626430
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ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni.2120
