The kinase GLK controls autoimmunity and NF-κB signaling by activating the kinase PKC-θ in T cells
The kinase GLK controls autoimmunity and NF-κB signaling by activating the kinase PKC-θ in T cells
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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The enzyme that directly activates the kinase PKC-θ during T cell antigen receptor signaling is still unknown. Tan and colleagues show that the serine-threonine kinase GLK is a direct activator of PKC-θ.
Protein kinase C-θ (PKC-θ) is required for activation of the transcription factor NF-κB induced by signaling via the T cell antigen receptor (T...
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The kinase GLK controls autoimmunity and NF-κB signaling by activating the kinase PKC-θ in T cells
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TN_cdi_proquest_miscellaneous_900630665
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_900630665
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ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni.2121