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The kinase GLK controls autoimmunity and NF-κB signaling by activating the kinase PKC-θ in T cells

The kinase GLK controls autoimmunity and NF-κB signaling by activating the kinase PKC-θ in T cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_900630665

The kinase GLK controls autoimmunity and NF-κB signaling by activating the kinase PKC-θ in T cells

About this item

Full title

The kinase GLK controls autoimmunity and NF-κB signaling by activating the kinase PKC-θ in T cells

Publisher

New York: Nature Publishing Group US

Journal title

Nature immunology, 2011-11, Vol.12 (11), p.1113-1118

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

The enzyme that directly activates the kinase PKC-θ during T cell antigen receptor signaling is still unknown. Tan and colleagues show that the serine-threonine kinase GLK is a direct activator of PKC-θ.
Protein kinase C-θ (PKC-θ) is required for activation of the transcription factor NF-κB induced by signaling via the T cell antigen receptor (T...

Alternative Titles

Full title

The kinase GLK controls autoimmunity and NF-κB signaling by activating the kinase PKC-θ in T cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_900630665

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_900630665

Other Identifiers

ISSN

1529-2908

E-ISSN

1529-2916

DOI

10.1038/ni.2121

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