Homocysteine-induced cardiomyocyte apoptosis and plasma membrane flip-flop are independent of S-aden...
Homocysteine-induced cardiomyocyte apoptosis and plasma membrane flip-flop are independent of S-adenosylhomocysteine: a crucial role for nuclear p47(phox)
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Netherlands
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English
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Netherlands
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We previously found that homocysteine (Hcy) induced plasma membrane flip-flop, apoptosis, and necrosis in cardiomyocytes. Inactivation of flippase by Hcy induced membrane flip-flop, while apoptosis was induced via a NOX2-dependent mechanism. It has been suggested that S-adenosylhomocysteine (SAH) is the main causative factor in hyperhomocysteinemia...
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Homocysteine-induced cardiomyocyte apoptosis and plasma membrane flip-flop are independent of S-adenosylhomocysteine: a crucial role for nuclear p47(phox)
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TN_cdi_proquest_miscellaneous_901006628
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_901006628
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1573-4919
DOI
10.1007/s11010-011-0973-4