Molecular basis of purine-rich RNA recognition by the human SR-like protein Tra2- beta 1
Molecular basis of purine-rich RNA recognition by the human SR-like protein Tra2- beta 1
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Full title
Molecular basis of purine-rich RNA recognition by the human SR-like protein Tra2- beta 1
Author / Creator
Journal title
Nature structural & molecular biology, 2011-04, Vol.18 (4), p.443-450
Language
English
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Scope and Contents
Contents
Tra2- beta 1 is a unique splicing factor as its single RNA recognition motif (RRM) is located between two RS (arginine-serine) domains. To understand how this protein recognizes its RNA target, we solved the structure of Tra2- beta 1 RRM in complex with RNA. The central 5'-AGAA-3' motif is specifically recognized by residues from the beta -sheet of...
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Full title
Molecular basis of purine-rich RNA recognition by the human SR-like protein Tra2- beta 1
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Record Identifier
TN_cdi_proquest_miscellaneous_902356698
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_902356698
Other Identifiers
ISSN
1545-9993
DOI
10.1038/nsmb.2001
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