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Wheat germ agglutinin enhanced cerebral uptake of anti-A[beta] antibody after intranasal administrat...

Wheat germ agglutinin enhanced cerebral uptake of anti-A[beta] antibody after intranasal administrat...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_902377663

Wheat germ agglutinin enhanced cerebral uptake of anti-A[beta] antibody after intranasal administration in 5XFAD mice

About this item

Full title

Wheat germ agglutinin enhanced cerebral uptake of anti-A[beta] antibody after intranasal administration in 5XFAD mice

Publisher

Kidlington: Elsevier Limited

Journal title

Vaccine, 2011-10, Vol.29 (44), p.7631-7637

Language

English

Formats

Publication information

Publisher

Kidlington: Elsevier Limited

More information

Scope and Contents

Contents

Highlights * WGA enhanced cerebral uptake and binding of anti-Aβ antibody to the native Aβ plaques. * WGA also facilitated intraneuronal penetration of anti-Aβ antibody. * WGA is a novel vehicle for maximizing intranasal passive immunization in Alzheimer's disease.

Alternative Titles

Full title

Wheat germ agglutinin enhanced cerebral uptake of anti-A[beta] antibody after intranasal administration in 5XFAD mice

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_902377663

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_902377663

Other Identifiers

ISSN

0264-410X

E-ISSN

1873-2518

DOI

10.1016/j.vaccine.2011.08.009

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