miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact wit...
miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4–NOT
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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The GW182 protein, which binds poly(A)-binding protein (PABP) and is part of the miRNA-induced silencing complex, effects translational repression and deadenylation of target mRNAs. New data indicate that GW182 independently interacts with the PAN2–PAN3 and CCR4–NOT deadenylase complexes and that interaction of GW182 with CCR4–NOT is PABP-independe...
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Full title
miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4–NOT
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TN_cdi_proquest_miscellaneous_902674892
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_902674892
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ISSN
1545-9993
E-ISSN
1545-9985
DOI
10.1038/nsmb.2149
