Comprehensive analysis of kinase inhibitor selectivity
Comprehensive analysis of kinase inhibitor selectivity
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Davis
et al
. extend their previous efforts to use inhibitor-kinase interactions to understand kinase inhibitor selectivity by profiling the binding of 72 kinase inhibitors to 442 human kinase catalytic domains. The data reveal group-specific differences in selectivity and suggest the feasibility of developing reasonably specific inhibitors f...
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Full title
Comprehensive analysis of kinase inhibitor selectivity
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TN_cdi_proquest_miscellaneous_903143802
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_903143802
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ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/nbt.1990