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Comprehensive analysis of kinase inhibitor selectivity

Comprehensive analysis of kinase inhibitor selectivity

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_903143802

Comprehensive analysis of kinase inhibitor selectivity

About this item

Full title

Comprehensive analysis of kinase inhibitor selectivity

Publisher

New York: Nature Publishing Group US

Journal title

Nature biotechnology, 2011-11, Vol.29 (11), p.1046-1051

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Davis
et al
. extend their previous efforts to use inhibitor-kinase interactions to understand kinase inhibitor selectivity by profiling the binding of 72 kinase inhibitors to 442 human kinase catalytic domains. The data reveal group-specific differences in selectivity and suggest the feasibility of developing reasonably specific inhibitors f...

Alternative Titles

Full title

Comprehensive analysis of kinase inhibitor selectivity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_903143802

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_903143802

Other Identifiers

ISSN

1087-0156

E-ISSN

1546-1696

DOI

10.1038/nbt.1990

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