A novel method for quantification of gemcitabine and its metabolites 2',2'-difluorodeoxyuridine and...
A novel method for quantification of gemcitabine and its metabolites 2',2'-difluorodeoxyuridine and gemcitabine triphosphate in tumour tissue by LC-MS/MS: comparison with (19)F NMR spectroscopy
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Publisher
Germany
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Language
English
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Publisher
Germany
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Contents
To develop a sensitive analytical method to quantify gemcitabine (2',2'-difluorodeoxycytidine, dFdC) and its metabolites 2',2'-difluorodeoxyuridine (dFdU) and 2',2'-difluorodeoxycytidine-5'-triphosphate (dFdCTP) simultaneously from tumour tissue.
Pancreatic ductal adenocarcinoma tumour tissue from genetically engineered mouse models of pancreati...
Alternative Titles
Full title
A novel method for quantification of gemcitabine and its metabolites 2',2'-difluorodeoxyuridine and gemcitabine triphosphate in tumour tissue by LC-MS/MS: comparison with (19)F NMR spectroscopy
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TN_cdi_proquest_miscellaneous_904220824
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_904220824
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ISSN
1432-0843
E-ISSN
1432-0843
DOI
10.1007/s00280-011-1613-0
