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Characterization of 64Cu-DOTA-conatumumab: a PET tracer for in vivo imaging of death receptor 5

Characterization of 64Cu-DOTA-conatumumab: a PET tracer for in vivo imaging of death receptor 5

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_904475695

Characterization of 64Cu-DOTA-conatumumab: a PET tracer for in vivo imaging of death receptor 5

About this item

Full title

Characterization of 64Cu-DOTA-conatumumab: a PET tracer for in vivo imaging of death receptor 5

Publisher

United States

Journal title

The Journal of nuclear medicine (1978), 2011-06, Vol.52 (6), p.942-949

Language

English

Formats

Publication information

Publisher

United States

More information

Scope and Contents

Contents

Conatumumab is a fully human monoclonal antibody that binds to and activates human death receptor 5 (DR5; also known as TRAIL receptor 2). The purpose of this study was to characterize (64)Cu-labeled conatumumab as a PET tracer for imaging DR5 in tumors.
DOTA-conatumumab was synthesized by incubating conatumumab with 2,2',2″-(10-(2-(2,5-dioxopyr...

Alternative Titles

Full title

Characterization of 64Cu-DOTA-conatumumab: a PET tracer for in vivo imaging of death receptor 5

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_904475695

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_904475695

Other Identifiers

ISSN

0161-5505

E-ISSN

1535-5667

DOI

10.2967/jnumed.110.086157

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