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A Mouse Mutation in the 12R-Lipoxygenase, Alox12b, Disrupts Formation of the Epidermal Permeability...

A Mouse Mutation in the 12R-Lipoxygenase, Alox12b, Disrupts Formation of the Epidermal Permeability...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_904477377

A Mouse Mutation in the 12R-Lipoxygenase, Alox12b, Disrupts Formation of the Epidermal Permeability Barrier

About this item

Full title

A Mouse Mutation in the 12R-Lipoxygenase, Alox12b, Disrupts Formation of the Epidermal Permeability Barrier

Publisher

Danvers, MA: Elsevier Inc

Journal title

Journal of investigative dermatology, 2007-08, Vol.127 (8), p.1893-1897

Language

English

Formats

Publication information

Publisher

Danvers, MA: Elsevier Inc

More information

Scope and Contents

Contents

Nonbullous congenital ichthyosiform erythroderma (NCIE) is a nonsyndromic form of autosomal recessive congenital ichthyosis characterized by hyperkeratosis and a disruption in the epidermal permeability barrier. Identification of mutations in two lipoxygenases (LOXs), ALOX12B (12R-LOX) and ALOXE3 (eLOX3), and further functional studies implicate AL...

Alternative Titles

Full title

A Mouse Mutation in the 12R-Lipoxygenase, Alox12b, Disrupts Formation of the Epidermal Permeability Barrier

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_904477377

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_904477377

Other Identifiers

ISSN

0022-202X

E-ISSN

1523-1747

DOI

10.1038/sj.jid.5700825

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