Log in to save to my catalogue

Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1

Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_904480309

Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1

About this item

Full title

Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2011-06, Vol.474 (7350), p.225-229

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Glis1 substitutes for c-Myc in stem-cell generation
Reprogramming of differentiated somatic cells to induced pluripotent stem (iPS) cells by exogenous expression of key transcription factors (Oct4, Sox2, Klf4 and c-Myc) has potential therapeutic applications. c-Myc enhances the efficiency of reprogramming, but the safety of using this oncogene h...

Alternative Titles

Full title

Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_904480309

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_904480309

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature10106

How to access this item