Improved long-term protection against Mycobacterium tuberculosis Beijing/W in mice after intra-derma...
Improved long-term protection against Mycobacterium tuberculosis Beijing/W in mice after intra-dermal inoculation of recombinant BCG expressing latency associated antigens
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Kidlington: Elsevier Ltd
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Language
English
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Kidlington: Elsevier Ltd
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Highlights► We show expression of latency-associated antigens by recombinant BCG improves longevity of protection against tuberculosis in a murine model. ► This improved protection was achieved against a representative of the medically-relevant Beijing/W lineage of Mycobacterium tuberculosis strains. ► This study provides a proof-of-principle that...
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Improved long-term protection against Mycobacterium tuberculosis Beijing/W in mice after intra-dermal inoculation of recombinant BCG expressing latency associated antigens
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TN_cdi_proquest_miscellaneous_904490899
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_904490899
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ISSN
0264-410X
E-ISSN
1873-2518
DOI
10.1016/j.vaccine.2011.07.144