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Induction of progressive glomerulonephritis by podocyte-specific overexpression of platelet-derived...

Induction of progressive glomerulonephritis by podocyte-specific overexpression of platelet-derived...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_907144091

Induction of progressive glomerulonephritis by podocyte-specific overexpression of platelet-derived growth factor-D

About this item

Full title

Induction of progressive glomerulonephritis by podocyte-specific overexpression of platelet-derived growth factor-D

Publisher

Basingstoke: Elsevier Inc

Journal title

Kidney international, 2011-12, Vol.80 (12), p.1292-1305

Language

English

Formats

Publication information

Publisher

Basingstoke: Elsevier Inc

More information

Scope and Contents

Contents

Platelet-derived growth factor-D (PDGF-D), normally expressed in podocytes, mediates mesangial cell proliferation in vivo. To study this further, we created transgenic mice with podocyte-specific overexpression of PDGF-D. Hemizygous mice were grossly indistinguishable from wild-type littermates through 11 months of age; however, hemizygous mice old...

Alternative Titles

Full title

Induction of progressive glomerulonephritis by podocyte-specific overexpression of platelet-derived growth factor-D

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_907144091

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_907144091

Other Identifiers

ISSN

0085-2538

E-ISSN

1523-1755

DOI

10.1038/ki.2011.278

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