Activation of Liver X Receptor Decreases BACE1 Expression and Activity by Reducing Membrane Choleste...
Activation of Liver X Receptor Decreases BACE1 Expression and Activity by Reducing Membrane Cholesterol Levels
About this item
Full title
Author / Creator
Cui, Weigang , Sun, Yan , Wang, Zhongping , Xu, Chongchong , Xu, Li , Wang, Fei , Chen, Zulin , Peng, Yuwen and Li, Ruixi
Publisher
Boston: Springer US
Journal title
Language
English
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Publication information
Publisher
Boston: Springer US
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Scope and Contents
Contents
The synthetic Liver X receptor (LXR) activator T0901317 has been reported to exert neuroprotective effect in Alzheimer’s disease, but the relationship between LXR activation and beta-site amyloid precursor protein cleaving enzyme 1 (BACE-1) remains uncertain. This study investigated the effect of T0901317 on membrane cholesterol levels, BACE1 expre...
Alternative Titles
Full title
Activation of Liver X Receptor Decreases BACE1 Expression and Activity by Reducing Membrane Cholesterol Levels
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_proquest_miscellaneous_907171690
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_907171690
Other Identifiers
ISSN
0364-3190
E-ISSN
1573-6903
DOI
10.1007/s11064-011-0513-3
