Structures of SAS-6 Suggest Its Organization in Centrioles
Structures of SAS-6 Suggest Its Organization in Centrioles
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Washington, DC: American Association for the Advancement of Science
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English
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Washington, DC: American Association for the Advancement of Science
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Centrioles are cylindrical, ninefold symmetrical structures with peripheral triplet microtubules strictly required to template cilia and flagella. The highly conserved protein SAS-6 constitutes the center of the cartwheel assembly that scaffolds centrioles early in their biogenesis. We determined the x-ray structure of the amino-terminal domain of...
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Structures of SAS-6 Suggest Its Organization in Centrioles
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TN_cdi_proquest_miscellaneous_907936364
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_907936364
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1199325
