Proteome Half-Life Dynamics in Living Human Cells
Proteome Half-Life Dynamics in Living Human Cells
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Publisher
Washington, DC: American Association for the Advancement of Science
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Language
English
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Publisher
Washington, DC: American Association for the Advancement of Science
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Contents
Cells remove proteins by two processes: degradation and dilution due to cell growth. The balance between these basic processes is poorly understood. We addressed this by developing an accurate and noninvasive method for measuring protein half-lives, called "bleach-chase," that is applicable to fluorescently tagged proteins. Assaying 100 proteins in...
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Full title
Proteome Half-Life Dynamics in Living Human Cells
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TN_cdi_proquest_miscellaneous_907944975
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_907944975
Other Identifiers
ISSN
0036-8075,1095-9203
E-ISSN
1095-9203
DOI
10.1126/science.1199784
