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Isolation of Single Human Hematopoietic Stem Cells Capable of Long-Term Multilineage Engraftment

Isolation of Single Human Hematopoietic Stem Cells Capable of Long-Term Multilineage Engraftment

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_907954293

Isolation of Single Human Hematopoietic Stem Cells Capable of Long-Term Multilineage Engraftment

About this item

Full title

Isolation of Single Human Hematopoietic Stem Cells Capable of Long-Term Multilineage Engraftment

Publisher

Washington, DC: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2011-07, Vol.333 (6039), p.218-221

Language

English

Formats

Publication information

Publisher

Washington, DC: American Association for the Advancement of Science

More information

Scope and Contents

Contents

Lifelong blood cell production is dependent on rare hematopoietic stem cells (HSCs) to perpetually replenish mature cells via a series of lineage-restricted intermediates. Investigating the molecular state of HSCs is contingent on the ability to purify HSCs away from transiently engrafting cells. We demonstrated that human HSCs remain infrequent, u...

Alternative Titles

Full title

Isolation of Single Human Hematopoietic Stem Cells Capable of Long-Term Multilineage Engraftment

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_907954293

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_907954293

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1201219

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