ZNRF1 promotes Wallerian degeneration by degrading AKT to induce GSK3B-dependent CRMP2 phosphorylati...
ZNRF1 promotes Wallerian degeneration by degrading AKT to induce GSK3B-dependent CRMP2 phosphorylation
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Wallerian degeneration is observed in many neurological disorders, and it is therefore important to elucidate the axonal degeneration mechanism to prevent, and further develop treatment for, such diseases. The ubiquitin–proteasome system (UPS) has been implicated in Wallerian degeneration, but the underlying molecular mechanism remains unclear. Her...
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ZNRF1 promotes Wallerian degeneration by degrading AKT to induce GSK3B-dependent CRMP2 phosphorylation
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TN_cdi_proquest_miscellaneous_908013406
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_908013406
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ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/ncb2373
