Rationale and design of the Treatment of Preserved Cardiac Function Heart Failure with an Aldosteron...
Rationale and design of the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist Trial: A randomized, controlled study of spironolactone in patients with symptomatic heart failure and preserved ejection fraction
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Author / Creator
Desai, Akshay S., MD, MPH , Lewis, Eldrin F., MD, MPH , Li, Rebecca, PhD , Solomon, Scott D., MD , Assmann, Susan F., PhD , Boineau, Robin, MD , Clausell, Nadine, MD , Diaz, Rafael, MD , Fleg, Jerome L., MD , Gordeev, Ivan, MD , McKinlay, Sonja, PhD , O'Meara, Eileen, MD , Shaburishvili, Tamaz, MD , Pitt, Bertram, MD and Pfeffer, Marc A., MD, PhD
Publisher
New York, NY: Elsevier Inc
Journal title
Language
English
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Publication information
Publisher
New York, NY: Elsevier Inc
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Scope and Contents
Contents
Background Despite increasing prevalence of heart failure (HF) in patients with preserved ejection fraction (PEF), there are no available therapies proven to reduce morbidity and mortality. Aldosterone, a potent stimulator of myocardial and vascular fibrosis, may be a key mediator of HF progression in this population and is therefore an important t...
Alternative Titles
Full title
Rationale and design of the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist Trial: A randomized, controlled study of spironolactone in patients with symptomatic heart failure and preserved ejection fraction
Authors, Artists and Contributors
Author / Creator
Lewis, Eldrin F., MD, MPH
Li, Rebecca, PhD
Solomon, Scott D., MD
Assmann, Susan F., PhD
Boineau, Robin, MD
Clausell, Nadine, MD
Diaz, Rafael, MD
Fleg, Jerome L., MD
Gordeev, Ivan, MD
McKinlay, Sonja, PhD
O'Meara, Eileen, MD
Shaburishvili, Tamaz, MD
Pitt, Bertram, MD
Pfeffer, Marc A., MD, PhD
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_908739647
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_908739647
Other Identifiers
ISSN
0002-8703
E-ISSN
1097-6744
DOI
10.1016/j.ahj.2011.09.007