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Rationale and design of the Treatment of Preserved Cardiac Function Heart Failure with an Aldosteron...

Rationale and design of the Treatment of Preserved Cardiac Function Heart Failure with an Aldosteron...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_908739647

Rationale and design of the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist Trial: A randomized, controlled study of spironolactone in patients with symptomatic heart failure and preserved ejection fraction

About this item

Full title

Rationale and design of the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist Trial: A randomized, controlled study of spironolactone in patients with symptomatic heart failure and preserved ejection fraction

Publisher

New York, NY: Elsevier Inc

Journal title

The American heart journal, 2011-12, Vol.162 (6), p.966-972.e10

Language

English

Formats

Publication information

Publisher

New York, NY: Elsevier Inc

More information

Scope and Contents

Contents

Background Despite increasing prevalence of heart failure (HF) in patients with preserved ejection fraction (PEF), there are no available therapies proven to reduce morbidity and mortality. Aldosterone, a potent stimulator of myocardial and vascular fibrosis, may be a key mediator of HF progression in this population and is therefore an important t...

Alternative Titles

Full title

Rationale and design of the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist Trial: A randomized, controlled study of spironolactone in patients with symptomatic heart failure and preserved ejection fraction

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_908739647

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_908739647

Other Identifiers

ISSN

0002-8703

E-ISSN

1097-6744

DOI

10.1016/j.ahj.2011.09.007

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