Stat3 as a Therapeutic Target for the Treatment of Psoriasis: A Clinical Feasibility Study with STA-...
Stat3 as a Therapeutic Target for the Treatment of Psoriasis: A Clinical Feasibility Study with STA-21, a Stat3 Inhibitor
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New York, NY: Elsevier Inc
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English
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New York, NY: Elsevier Inc
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Epidermal keratinocytes in psoriatic lesions are characterized by activated Stat3, and increased levels of cytokines and growth factors that promote Stat3 activation have been found within psoriatic lesions. K5.Stat3C transgenic mice, in which keratinocytes express a constitutively active Stat3, develop psoriasis-like skin lesions. In this study, w...
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Stat3 as a Therapeutic Target for the Treatment of Psoriasis: A Clinical Feasibility Study with STA-21, a Stat3 Inhibitor
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TN_cdi_proquest_miscellaneous_911149087
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_911149087
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ISSN
0022-202X,1523-1747
E-ISSN
1523-1747
DOI
10.1038/jid.2010.255
