Evidence for a Pathophysiological Role of Keratinocyte-Derived Type III Interferon (IFNλ) in Cutaneo...
Evidence for a Pathophysiological Role of Keratinocyte-Derived Type III Interferon (IFNλ) in Cutaneous Lupus Erythematosus
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New York, NY: Elsevier Inc
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English
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New York, NY: Elsevier Inc
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Type I IFNs (IFNα/β) have been shown to have a central role in the pathophysiology of lupus erythematosus (LE). The recently discovered type III IFNs (IFNλ1/IL29, IFNλ2/IL28a, IFNλ3/IL28b) share several functional similarities with type I IFNs, particularly in antiviral immunity. As IFNλs act primarily on epithelial cells, we investigated whether t...
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Evidence for a Pathophysiological Role of Keratinocyte-Derived Type III Interferon (IFNλ) in Cutaneous Lupus Erythematosus
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TN_cdi_proquest_miscellaneous_911150066
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_911150066
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ISSN
0022-202X
E-ISSN
1523-1747
DOI
10.1038/jid.2010.244