Cetuximab induces mitochondrial translocalization of EGFRvIII, but not EGFR: involvement of mitochon...
Cetuximab induces mitochondrial translocalization of EGFRvIII, but not EGFR: involvement of mitochondria in tumor drug resistance?
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Publisher
Dordrecht: Springer Netherlands
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Language
English
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Dordrecht: Springer Netherlands
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Contents
Dysregulation of growth factor receptors such as the epidermal growth factor receptor (EGFR) and of its truncated form EGFRvIII is frequently found in human tumors. EGFRvIII is a promising target for selective molecular tumor therapy because it is exclusively expressed by tumor cells. Cetuximab/Erbitux is a monoclonal antibody which targets EGFR an...
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Full title
Cetuximab induces mitochondrial translocalization of EGFRvIII, but not EGFR: involvement of mitochondria in tumor drug resistance?
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TN_cdi_proquest_miscellaneous_911942985
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_911942985
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ISSN
1010-4283
E-ISSN
1423-0380
DOI
10.1007/s13277-011-0248-4
