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TRPA1 channels regulate astrocyte resting calcium and inhibitory synapse efficacy through GAT-3

TRPA1 channels regulate astrocyte resting calcium and inhibitory synapse efficacy through GAT-3

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_912641598

TRPA1 channels regulate astrocyte resting calcium and inhibitory synapse efficacy through GAT-3

About this item

Full title

TRPA1 channels regulate astrocyte resting calcium and inhibitory synapse efficacy through GAT-3

Publisher

New York: Nature Publishing Group US

Journal title

Nature neuroscience, 2012-01, Vol.15 (1), p.70-80

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Using a membrane-tethered, genetically encoded Ca
2+
indicator, the authors describe a novel Ca
2+
signal in hippocampal astrocytes. These 'spotty' Ca
2+
signals were found to be mediated by astrocytic TRPA1 channels. Decreasing astrocyte resting Ca
2+
, regulated by TRPA1 channels, decreased interneuron inhibitory synapse e...

Alternative Titles

Full title

TRPA1 channels regulate astrocyte resting calcium and inhibitory synapse efficacy through GAT-3

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_912641598

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_912641598

Other Identifiers

ISSN

1097-6256,1546-1726

E-ISSN

1546-1726

DOI

10.1038/nn.3000

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