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Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell...

Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_912917667

Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell renal cell carcinoma

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Huanming Yang, Zhiming Cai, Jun Wang and colleagues report whole-exome sequencing of 10 clear cell renal cell carcinomas followed by a screen of ~1,100 genes in a total of 98 tumors. They found 12 new disease-associated genes and detected frequent alterations in the ubiquitin-mediated proteolysis pathway.
We sequenced whole exomes of ten clear c...

Alternative Titles

Full title

Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell renal cell carcinoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_912917667

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_912917667

Other Identifiers

ISSN

1061-4036

E-ISSN

1546-1718

DOI

10.1038/ng.1014

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