Higher CD3+ and CD34+ cell doses in the graft increase the incidence of acute GVHD in children recei...
Higher CD3+ and CD34+ cell doses in the graft increase the incidence of acute GVHD in children receiving BMT for thalassemia
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Author / Creator
Gaziev, J , Isgrò, A , Marziali, M , Daniele, N , Gallucci, C , Sodani, P , Simone, M D , Adorno, G , Paciaroni, K , Andreani, M , Lanti, A , Del Proposto, G , Testi, M , De Angelis, G , Roveda, A , Alfieri, C , Saltarelli, F and Lucarelli, G
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
We evaluated the incidence of GVHD, risk factors and the impact of graft composition on acute GVHD (aGVHD) in 92 children who underwent BMT for thalassemia following busulfan/cyclophosphamide (BUCY)-based conditioning regimens and GVHD prophylaxis with CSA/short-MTX and methylprednisolone. The incidence of grade 2–4 and 3–4 aGVHD was 35% (95% confi...
Alternative Titles
Full title
Higher CD3+ and CD34+ cell doses in the graft increase the incidence of acute GVHD in children receiving BMT for thalassemia
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Record Identifier
TN_cdi_proquest_miscellaneous_915632332
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_915632332
Other Identifiers
ISSN
0268-3369
E-ISSN
1476-5365
DOI
10.1038/bmt.2011.3
