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RAF around the Edges — The Paradox of BRAF Inhibitors

RAF around the Edges — The Paradox of BRAF Inhibitors

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_917158963

RAF around the Edges — The Paradox of BRAF Inhibitors

About this item

Full title

RAF around the Edges — The Paradox of BRAF Inhibitors

Author / Creator

Publisher

United States: Massachusetts Medical Society

Journal title

The New England journal of medicine, 2012-01, Vol.366 (3), p.271-273

Language

English

Formats

Publication information

Publisher

United States: Massachusetts Medical Society

More information

Scope and Contents

Contents

The recent success of BRAF inhibitors represents a great stride forward for melanoma research. When used to treat patients with melanoma who harbor the
BRAF V600E
mutation, these inhibitors lead to the remission of even advanced lesions. However, resistance to BRAF inhibitors emerges within months. Of added concern is the development of secon...

Alternative Titles

Full title

RAF around the Edges — The Paradox of BRAF Inhibitors

Authors, Artists and Contributors

Author / Creator

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_917158963

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_917158963

Other Identifiers

ISSN

0028-4793

E-ISSN

1533-4406

DOI

10.1056/NEJMe1111636

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