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Skeletal muscle transcriptional coactivator PGC-1α mediates mitochondrial, but not metabolic, change...

Skeletal muscle transcriptional coactivator PGC-1α mediates mitochondrial, but not metabolic, change...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_923192091

Skeletal muscle transcriptional coactivator PGC-1α mediates mitochondrial, but not metabolic, changes during calorie restriction

About this item

Full title

Skeletal muscle transcriptional coactivator PGC-1α mediates mitochondrial, but not metabolic, changes during calorie restriction

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2012-02, Vol.109 (8), p.2931-2936

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Calorie restriction (CR) is a dietary intervention that extends lifespan and healthspan in a variety of organisms. CR improves mitochondrial energy production, fuel oxidation, and reactive oxygen species (ROS) scavenging in skeletal muscle and other tissues, and these processes are thought to be critical to the benefits of CR. PGC-1α is a transcrip...

Alternative Titles

Full title

Skeletal muscle transcriptional coactivator PGC-1α mediates mitochondrial, but not metabolic, changes during calorie restriction

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_923192091

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_923192091

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1115813109

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