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IgG from Patients with Bullous Pemphigoid Depletes Cultured Keratinocytes of the 180-kDa Bullous Pem...

IgG from Patients with Bullous Pemphigoid Depletes Cultured Keratinocytes of the 180-kDa Bullous Pem...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_923196591

IgG from Patients with Bullous Pemphigoid Depletes Cultured Keratinocytes of the 180-kDa Bullous Pemphigoid Antigen (Type XVII Collagen) and Weakens Cell Attachment

About this item

Full title

IgG from Patients with Bullous Pemphigoid Depletes Cultured Keratinocytes of the 180-kDa Bullous Pemphigoid Antigen (Type XVII Collagen) and Weakens Cell Attachment

Publisher

New York, NY: Elsevier Inc

Journal title

Journal of investigative dermatology, 2009-04, Vol.129 (4), p.919-926

Language

English

Formats

Publication information

Publisher

New York, NY: Elsevier Inc

More information

Scope and Contents

Contents

We have shown that binding of bullous pemphigoid (BP)-patient IgG (BP-IgG) causes the internalization of BP180 from the cell membrane. This study examined whether BP-IgG treatment can deplete cultured keratinocytes of BP180, how it affects cellular levels of α6 and β4 integrins (by western blot analysis using monoclonal antibodies to these antigens...

Alternative Titles

Full title

IgG from Patients with Bullous Pemphigoid Depletes Cultured Keratinocytes of the 180-kDa Bullous Pemphigoid Antigen (Type XVII Collagen) and Weakens Cell Attachment

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_923196591

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_923196591

Other Identifiers

ISSN

0022-202X

E-ISSN

1523-1747

DOI

10.1038/jid.2008.305

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