Identification of Id1-DBL2X of VAR2CSA as a key domain inducing highly inhibitory and cross-reactive...
Identification of Id1-DBL2X of VAR2CSA as a key domain inducing highly inhibitory and cross-reactive antibodies
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Publisher
Netherlands: Elsevier Ltd
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Language
English
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Publisher
Netherlands: Elsevier Ltd
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Contents
Highlights ► VAR2CSA is the main candidate for a vaccine against pregnancy-associated malaria. ► We performed a VAR2CSA antigenic mapping to identify the shortest fragment carrying major protective epitopes. ► Id1-DBL2X is the shortest region inducing antibodies that fully block infected erythrocytes adhesion to CSA. ► Anti-Id1-DBL2X inhibitory ant...
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Full title
Identification of Id1-DBL2X of VAR2CSA as a key domain inducing highly inhibitory and cross-reactive antibodies
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TN_cdi_proquest_miscellaneous_923202738
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_923202738
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ISSN
0264-410X
E-ISSN
1873-2518
DOI
10.1016/j.vaccine.2011.12.065
