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CLASPs prevent irreversible multipolarity by ensuring spindle-pole resistance to traction forces dur...

CLASPs prevent irreversible multipolarity by ensuring spindle-pole resistance to traction forces dur...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_925717259

CLASPs prevent irreversible multipolarity by ensuring spindle-pole resistance to traction forces during chromosome alignment

About this item

Full title

CLASPs prevent irreversible multipolarity by ensuring spindle-pole resistance to traction forces during chromosome alignment

Publisher

London: Nature Publishing Group UK

Journal title

Nature cell biology, 2012-03, Vol.14 (3), p.295-303

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The formation of a bipolar spindle is critical for accurate segregation of the genome. Maiato and colleagues now demonstrate that CLASPs (cytoplasmic linker associated proteins) prevent spindle multipolarity in a manner independent of end-on kinetochore–microtubule attachments. They propose that CENP-E-mediated traction forces are balanced by CLASP...

Alternative Titles

Full title

CLASPs prevent irreversible multipolarity by ensuring spindle-pole resistance to traction forces during chromosome alignment

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_925717259

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_925717259

Other Identifiers

ISSN

1465-7392

E-ISSN

1476-4679

DOI

10.1038/ncb2423

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