Methylglyoxal, glyoxalase 1 and the dicarbonyl proteome
Methylglyoxal, glyoxalase 1 and the dicarbonyl proteome
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Publisher
Vienna: Springer Vienna
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Language
English
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Vienna: Springer Vienna
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Contents
Methylglyoxal (MG) is a potent protein glycating agent. Glycation is directed to guanidino groups of arginine residues forming mainly hydroimidazolone
N
δ
-(5-hydro-5-methyl-4-imidazolon-2-yl)-ornithine (MG-H1) residues. MG-H1 formation is damaging to the proteome as modification is often directed to functionally important arginine residue...
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Full title
Methylglyoxal, glyoxalase 1 and the dicarbonyl proteome
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TN_cdi_proquest_miscellaneous_926876934
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_926876934
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ISSN
0939-4451
E-ISSN
1438-2199
DOI
10.1007/s00726-010-0783-0