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Homeostatic responses by surviving cortical pyramidal cells in neurodegenerative tauopathy

Homeostatic responses by surviving cortical pyramidal cells in neurodegenerative tauopathy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_926886838

Homeostatic responses by surviving cortical pyramidal cells in neurodegenerative tauopathy

About this item

Full title

Homeostatic responses by surviving cortical pyramidal cells in neurodegenerative tauopathy

Publisher

Berlin/Heidelberg: Springer-Verlag

Journal title

Acta neuropathologica, 2011-11, Vol.122 (5), p.551-564

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer-Verlag

More information

Scope and Contents

Contents

Cortical neuron death is prevalent by 9 months in rTg(tau
P301L
)4510 tau mutant mice (TG) and surviving pyramidal cells exhibit dendritic regression and spine loss. We used whole-cell patch-clamp recordings to investigate the impact of these marked structural changes on spontaneous excitatory and inhibitory postsynaptic currents (sEPSCs and...

Alternative Titles

Full title

Homeostatic responses by surviving cortical pyramidal cells in neurodegenerative tauopathy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_926886838

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_926886838

Other Identifiers

ISSN

0001-6322

E-ISSN

1432-0533

DOI

10.1007/s00401-011-0877-0

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