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Proteolytic activation of the epithelial sodium channel and therapeutic application of a serine prot...

Proteolytic activation of the epithelial sodium channel and therapeutic application of a serine prot...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_927687837

Proteolytic activation of the epithelial sodium channel and therapeutic application of a serine protease inhibitor for the treatment of salt-sensitive hypertension

About this item

Full title

Proteolytic activation of the epithelial sodium channel and therapeutic application of a serine protease inhibitor for the treatment of salt-sensitive hypertension

Publisher

Japan: Springer Japan

Journal title

Clinical and experimental nephrology, 2012-02, Vol.16 (1), p.44-48

Language

English

Formats

Publication information

Publisher

Japan: Springer Japan

More information

Scope and Contents

Contents

Proteases are involved in numerous essential biological processes including blood clotting, controlled cell death, and tissue differentiation. Prostasin, a glycosylphosphatidylinositol-anchored serine protease, has been identified as a potential regulator of the epithelial sodium channel (ENaC) function in the kidney, lung, and airways. ENaC is com...

Alternative Titles

Full title

Proteolytic activation of the epithelial sodium channel and therapeutic application of a serine protease inhibitor for the treatment of salt-sensitive hypertension

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_927687837

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_927687837

Other Identifiers

ISSN

1342-1751

E-ISSN

1437-7799

DOI

10.1007/s10157-011-0506-1

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