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Association of aureolic acid antibiotic, chromomycin A3 with Cu2+ and its negative effect upon DNA b...

Association of aureolic acid antibiotic, chromomycin A3 with Cu2+ and its negative effect upon DNA b...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_927991675

Association of aureolic acid antibiotic, chromomycin A3 with Cu2+ and its negative effect upon DNA binding property of the antibiotic

About this item

Full title

Association of aureolic acid antibiotic, chromomycin A3 with Cu2+ and its negative effect upon DNA binding property of the antibiotic

Publisher

Dordrecht: Springer Netherlands

Journal title

Biometals, 2012-04, Vol.25 (2), p.435-450

Language

English

Formats

Publication information

Publisher

Dordrecht: Springer Netherlands

More information

Scope and Contents

Contents

Here we have examined the association of an aureolic acid antibiotic, chromomycin A3 (CHR), with Cu
2+
. CHR forms a high affinity 2:1 (CHR:Cu
2+
) complex with dissociation constant of 0.08 × 10
−10
 M
2
at 25°C, pH 8.0. The affinity of CHR for Cu
2+
is higher than those for Mg
2+
and Zn
2+
reported earlie...

Alternative Titles

Full title

Association of aureolic acid antibiotic, chromomycin A3 with Cu2+ and its negative effect upon DNA binding property of the antibiotic

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_927991675

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_927991675

Other Identifiers

ISSN

0966-0844

E-ISSN

1572-8773

DOI

10.1007/s10534-011-9516-4

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