Identification of novel potential HIF-prolyl hydroxylase inhibitors by in silico screening
Identification of novel potential HIF-prolyl hydroxylase inhibitors by in silico screening
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Publisher
Dordrecht: Springer Netherlands
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Language
English
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Publisher
Dordrecht: Springer Netherlands
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Scope and Contents
Contents
Suppression of HIF-prolyl hydroxylase (PHD) activity by small-molecule inhibitors leads to the stabilization of hypoxia inducible factor and has been recognized as promising drug target for the treatment of ischemic diseases. In this study, pharmacophore-based virtual screening and molecular docking approaches were concurrently used with suitable m...
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Full title
Identification of novel potential HIF-prolyl hydroxylase inhibitors by in silico screening
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TN_cdi_proquest_miscellaneous_929122440
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_929122440
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ISSN
1381-1991,1573-501X
E-ISSN
1573-501X
DOI
10.1007/s11030-011-9338-x
