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Effect of a Monoclonal Antibody to PCSK9 on LDL Cholesterol

Effect of a Monoclonal Antibody to PCSK9 on LDL Cholesterol

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_940835703

Effect of a Monoclonal Antibody to PCSK9 on LDL Cholesterol

About this item

Full title

Effect of a Monoclonal Antibody to PCSK9 on LDL Cholesterol

Publisher

Waltham, MA: Massachusetts Medical Society

Journal title

The New England journal of medicine, 2012-03, Vol.366 (12), p.1108-1118

Language

English

Formats

Publication information

Publisher

Waltham, MA: Massachusetts Medical Society

More information

Scope and Contents

Contents

A monoclonal antibody to PCSK9 was studied in two single-dose trials in healthy volunteers and one multiple-dose trial in patients with familial or nonfamilial hypercholesterolemia. In all three groups, the antibody reduced levels of LDL cholesterol.
In 2003, Abifadel and colleagues
1
described two families with autosomal dominant hypercho...

Alternative Titles

Full title

Effect of a Monoclonal Antibody to PCSK9 on LDL Cholesterol

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_940835703

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_940835703

Other Identifiers

ISSN

0028-4793

E-ISSN

1533-4406

DOI

10.1056/NEJMoa1105803

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