Effect of a Monoclonal Antibody to PCSK9 on LDL Cholesterol
Effect of a Monoclonal Antibody to PCSK9 on LDL Cholesterol
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Publisher
Waltham, MA: Massachusetts Medical Society
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Language
English
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Publisher
Waltham, MA: Massachusetts Medical Society
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Scope and Contents
Contents
A monoclonal antibody to PCSK9 was studied in two single-dose trials in healthy volunteers and one multiple-dose trial in patients with familial or nonfamilial hypercholesterolemia. In all three groups, the antibody reduced levels of LDL cholesterol.
In 2003, Abifadel and colleagues
1
described two families with autosomal dominant hypercho...
Alternative Titles
Full title
Effect of a Monoclonal Antibody to PCSK9 on LDL Cholesterol
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TN_cdi_proquest_miscellaneous_940835703
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_940835703
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa1105803