Limited effects of frequent CYP2D636-10 tandem duplication allele on in vivo dextromethorphan metabo...
Limited effects of frequent CYP2D636-10 tandem duplication allele on in vivo dextromethorphan metabolism in a Japanese population
About this item
Full title
Author / Creator
Publisher
Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag
Subjects
More information
Scope and Contents
Contents
Purpose Although CYP2D6*36 was thought to be one of the alleles causing the poor metabolizer phenotype, several in vitro studies clarified that the enzyme produced by CYP2D6*36 showed enzymatic activities. However, the effects of CYP2D6*36 in tandem with CYP2D6*10 on the in vivo CYP2D6 activity have been unclear. In this study, we investigated in v...
Alternative Titles
Full title
Limited effects of frequent CYP2D636-10 tandem duplication allele on in vivo dextromethorphan metabolism in a Japanese population
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_954578176
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_954578176
Other Identifiers
ISSN
0031-6970
E-ISSN
1432-1041
DOI
10.1007/s00228-010-0876-4
