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Pharmacologic reversal of neurogenic and neuroplastic abnormalities and cognitive impairments withou...

Pharmacologic reversal of neurogenic and neuroplastic abnormalities and cognitive impairments withou...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_954596688

Pharmacologic reversal of neurogenic and neuroplastic abnormalities and cognitive impairments without affecting Aβ and tau pathologies in 3xTg-AD mice

About this item

Full title

Pharmacologic reversal of neurogenic and neuroplastic abnormalities and cognitive impairments without affecting Aβ and tau pathologies in 3xTg-AD mice

Publisher

Berlin/Heidelberg: Springer-Verlag

Journal title

Acta neuropathologica, 2010-11, Vol.120 (5), p.605-621

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer-Verlag

More information

Scope and Contents

Contents

In addition to the occurrence of numerous neurofibrillary tangles and Aβ plaques, neurogenesis and neuronal plasticity are markedly altered in Alzheimer disease (AD). Although the most popular therapeutic approach has been to inhibit neurodegeneration, another is to promote neurogenesis and neuronal plasticity by utilizing the regenerative capacity...

Alternative Titles

Full title

Pharmacologic reversal of neurogenic and neuroplastic abnormalities and cognitive impairments without affecting Aβ and tau pathologies in 3xTg-AD mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_954596688

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_954596688

Other Identifiers

ISSN

0001-6322

E-ISSN

1432-0533

DOI

10.1007/s00401-010-0734-6

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